Author：Zhu Ni

Abstract： Objective To understand the incidence trend and epidemiological characteristics of COVID-19 in Shaanxi province. Methods The incidence data of COVID-19 reported in Shaanxi as of 22 February, 2020 were collected for an epidemiological descriptive analysis. Results A total of 245 confirmed cases of COVID-19 were reported in Shaanxi. Most cases were mild (87.76%). As time passed, the areas where confirmed cases were reported continued to increase. The case number in Xi’an was highest, accounting for nearly half of the total reported cases in the province. The epidemic pattern in Shaanxi had gradually shifted from imported case pattern to local case pattern, and the transmission of local cases was mainly based on family cluster transmission. The confirmed cases from different sources had caused the secondary transmission in Shaanxi. After February 7, the number of reported cases began to fluctuate and decrease stably, indicating a decrease-to-zero period. Conclusions At present, the overall epidemic of COVID-19 in Shaanxi has gradually been mitigated. However, considering the approaching of return to work and study and the increasing of imported cases from other countries, the prevention and control of COVIS-19 in Shaanxi will face new challenges.

Journal：Chinese Journal of Epidemiology

Publishing Time：2020,41(00):E034-E034

DOI：10.3760/cma.j.cn112338-20200225-00172

Author：Wang Li

Abstract：The patient was 3 years and 3 months old, from Wuhan, Hubei Province. He was admitted to the people's Hospital of Sheqi County, Nanyang City for 2 days due to fever and diarrhea. His father was diagnosed as COVID-19 2 days ago after returning the county 9 days ago. The children with symptoms and signs had fever, the temperature fluctuated in 37.0-38.7 ℃, accompanied by diarrhea, and the stool was yellow green loose stool, 2-3 times a day, with large amount. No mucus and pus, no abdominal pain and vomiting, no convulsions and consciousness disorders. Physical examination showed no positive signs except pharyngeal congestion. On the second day after admission, the body temperature was normal, diarrhea was relieved and mild cough appeared. The COVID-19 diagnosis and treatment plan (Trial Version Fifth) was used for diagnosis, and the nasal swabs, swabs and nucleic acids were detected on the second day after admission. All the results were positive, and the lung CT showed a low luminance of the left lower lung, which was confirmed to be COVID-19 infection. During the treatment, the patients were given antiviral (interferon α - 2b atomization, ribavirin injection intravenous drip), oral Bifidobacterium tetrad live bacteria to regulate the intestinal flora, fructose diphosphate to protect the myocardium and other symptomatic support treatment. The clinical symptoms disappeared on the 9th day after the clinical outcome, but the nucleic acid test was still positive. On the 18th and 19th day after admission, the nasal swab, pharyngeal swab and serum nucleic acid test turned negative for two consecutive times, reaching the discharge standard. Suggested People: Paediatrics;Department of respiration

Journal：Chinese Medical Case Repository

Publishing Time：2020,02(01):E021-E021

DOI：10.3760/cma.j.cmcr.2020.e00018

Author：Kiesha Prem

Abstract：

Journal：柳叶刀·公共卫生

Publishing Time：

DOI：10.1016/ S2468-2667(20)30073-6

Author：Esteban A. Hernandez-Vargas

Abstract：

Journal：medrxiv

Publishing Time：12-7月-05

DOI：10.1101/2020.03.26.20044487

Author：Kate Sweeny

Abstract：

Journal：psychology archive

Publishing Time：eprint

DOI：10.31234/osf.io/e3kcw

Author：Jie Liu

Abstract：

Journal：柳叶刀·传染病

Publishing Time：

DOI：10.2139/ssrn.3555247

Author： Gou Faxiang

Abstract： Objective To understand the epidemiological characteristics of COVID-19 cases in different epidemic stages in Gansu province. Methods Epidemiological investigation was conducted to collect the information of confirmed COVID-19 cases, including demographic, epidemiological and clinical information. Results As of 25 February 2020, a total of 91 confirmed COVID-19 cases had been reported in Gansu. The epidemic of COVID-19 in Gansu can be divided as three different stages, i.e. imported case stage, imported-case plus indigenous case stage, and indigenous case stage. A total of 63 cases were clustered cases (69.23%), 3 cases were medical staff infected with non-occupational exposure. The initial symptoms included fever (54.95%, 50/91), cough (52.75%, 48/91), or fatigue (28.57%, 26/91), the proportion of each symptom showed a decreasing trend along with the three epidemic stages, but only the differences in proportions of fever (trend χ 2 =2.20, P <0.05) and fatigue (trend χ 2 =3.18, P <0.05) among the three epidemic stages were statistically significant. The cases with critical severe symptoms accounted for 42.85% (6/14), 23.73% (14/59) and 16.67% (3/18), respectively, in three epidemic stages, showed a decreasing trend ( H =6.45, P <0.05). Also, the incubation period prolonged along with the epidemic stage ( F =51.65, P <0.01), but the intervals between disease onset and hospital visit ( F =5.32, P <0.01), disease onset and diagnosis ( F =5.25, P <0.01) became shorter along with the epidemic stage. Additionally, the basic reproduction number (R0) had decreased from 2.61 in imported case stage to 0.66 in indigenous case stage. Conclusions The COVID-19 epidemic in Gansu was caused by the imported cases, and about 2/3 cases were clustered ones. No medical worker was observed to be infected by occupational exposure. With the progression of COVID-19 epidemic in Gansu, the change in initial symptom and incubation period suggests, the early screening cannot only depend on body temperature monitoring.

Journal：Chinese Journal of Epidemiology

Publishing Time：2020,41:E032-E032

DOI：10.3760/cma.j.cn112338-20200229-00216

Author： Xiao Wenjia

Abstract： Objective To analyze the epidemiological characteristics of a cluster of 5 confirmed COVID?19 cases related with the transmission in incubation period of initial case, and find out the infection source and transmission chain.. Methods According to 'The Prevention?and?Control Protocol for Coronavirus Disease 2019 (Third Edition)' issued by the National Health Commission, a field epidemiological survey was conducted for the 5 cases in January 2020. Nasopharyngeal swabs and sputum samples were collected from them for the detection of 2019-nCoV by real time RT-PCR. Multi prevention and control measures were taken, such as tracking and screening close contacts, medical isolation observation, investigating the epidemiological link, analyzing transmission chain. Results Case 1, who had common environmental exposure with other COVID?19 cases, got sick on 20 January, 2020 and was confirmed on 1 February. Case 2 became symptomatic on 22 January and was confirmed on 27 January. Case 3 got sick on 25 January and was confirmed on 30 January. Case 4 had illness onset on 20 January and was confirmed on 1 February. Case 5 got sick on 23 January and was confirmed on 31 January. Among the 5 cases, case 2 died and the illness of other cases were effectively controlled. After exclusion of other common exposure factors, case 1 had a 6-hour meeting with case 2 and case 3 on 19 January. Case 2 and case 3 might be infected by case 1 during the incubation period. It is the key point for epidemiological investigation. Conclusion The epidemiological investigation indicates that the transmission might occur in the incubation period of COVID-19 case, close attention should be paid to it in future COVID-19 prevention and control.

Journal：Chinese Journal of Epidemiology

Publishing Time：2020,41:E033-E033

DOI：10.3760/cma.j.cn112338-20200302-00236

Author：Hamid Reza Niazkar

Abstract：

Journal：Asian Pacific Journal of Tropical Medicine

Publishing Time：2020; 13(4): 185-186

DOI：10.4103/1995-7645.280234

Author：Joseph R. Fauver

Abstract：

Journal：medRxiv

Publishing Time：12-7月-05

DOI：10.1101/2020.03.25.20043828

Author：Hong Hong Pu

Abstract：

Journal：medRxiv

Publishing Time：

DOI：10.1101/2020.03.20.20038679

Author：George J Milne

Abstract：

Journal：medRxiv

Publishing Time：12-7月-05

DOI：10.1101/2020.03.20.20040055

Author：

Abstract：

Journal：Infection control and hospital epidemiology

Publishing Time：

DOI：10.1017/ice.2020.99